Cambridge Healthtech Institute, San Diego, California
21 - 22 March, 2007
In recent years a relatively large number of novel essential targets have been proposed by using genomics and bioinformatics approaches as well as technologies, such as high-throughput screening and sequencing, which have clearly played a key role in identifying leads for optimization. To successfully tackle the antibacterial resistance, novel targets are only part of the equation. Challenges that also need to be addressed are topics such as predicting toxicology, selectivity, resistance, permeability and pk of a new lead and creating new models for optimization of leads and compounds. This conference is designed to bring together top level scientists from the academic, pharmaceutical and biotech area to define and refine the path of developing novel antibacterials. Topics to be covered in this conference:
• Bacterial Genomics and Informatics
• Bacterial Selectivity
• Screening for Novel Antibacterials
• Natural Products
• Chemical Sources
• Tackling the Challenge of Resistance
• Lead Optimization from Chemical and Biological Perspectives
• Novel Technologies and Drug Design
• Structure Based Drug Design
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