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The Macrophage: Homeostasis, Immunoregulation and Disease

 
  June 16, 2006  
     
 


Keystone Symposia, Copper Mountain, Colorado
April 11 - 16, 2007


Macrophage-like cells are present in essentially all metazoans. Although often dismissed merely as scavengers, recent genetic, molecular, cellular, and in vivo insights into macrophage biology have focused mechanistic attention on their prodigiously varied roles: as sensors, effectors and regulators of innate immunity; as links between innate and adaptive immunity; as cells central to tissue development and homeostasis; as targets of diverse pathogens; and as cells integral to the pathogenesis of a variety of infectious and non-infectious diseases. Investigation into this profusion of roles has revealed startling conservation of underlying molecular themes and mechanisms, a growing understanding that forms the basis for the organization of this meeting. A special focus of the meeting will be on areas of macrophage biology that are usually neglected, including macrophage differentiation and heterogeneity, and their trophic and developmental roles. The meeting is intended to provide a state-of-the-art overview of macrophage biology, to highlight the translational implications of this work, to provide scientific "cross-fertilization" across different model systems, topics and levels of investigation, and to help define the most important questions to be addressed next in the field.
 
 
Organized by: Christopher L. Karp, Stefanie N. Vogel and Siamon Gordon
Invited Speakers: - Jessica Bell, National Institutes of Health
- Frank Brombacher, University of Cape Town
- Gordon Brown, University of Cape Town
- Israel Charo, Gladstone Institute of Cardiovascular Disease
- Janice Clements, Johns Hopkins University
- Michel Desjardins, University of Montreal
- Ronald Evans, The Salk Institute
- Kate Fitzgerald, University of Massachusetts Medical School
- Frederic Geissmann, Necker
- Christopher Glass, University of California, San Diego
- Siamon Gordon, University of Oxford
- David Greaves, University of Oxford
- Sergio Grinstein, Hospital for Sick Children
- Christopher Karp, Cincinnati Children's Hospital Research Foundation
- Richard Lang, Cincinnati Children's Hospital Medical Center
- Paul Martin, University of Bristol
- Luisa Martinez-Pomares, University of Nottingham
- David Mosser, University of Maryland
- Harald Neumann, University Bonn
- Luke O'Neill, Trinity College Dublin
- Edgar Pick, Tel Aviv University
- Jeffrey Pollard, Albert Einstein College of Medicine
- Richard Ransohoff, Cleveland Clinic Foundation
- F. Sher, NIAID, National Institutes of Health
- Jennifer Stow, University of Queensland
- Michele Swanson, University of Michigan Medical School
- Jenny Ting, University of North Carolina
- Agnes Vignery, Yale School of Medicine
- Stefanie Vogel, University of Maryland
- Jeffrey Whitsett, Cincinnati Children's Hospital Medical Center
- Thomas Wynn, National Institutes of Health
 
Deadline for Abstracts: Dec. 11, 2006
 
Registration: Please see website
E-mail: info@keystonesymposia.org
 
   
 
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