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Imaging Immune Responses

 
  June 15, 2006  
     
 


Keystone Symposia, Keystone, Colorado
February 25 - March 1, 2007


The cellular events leading to host defense and immunopathology are dynamic in nature and involve the migration, transient arrest, and redistribution of various hematopoietic cells types between blood, secondary lymphoid organs, and peripheral tissues. For this reason, a great deal of excitement has been generated by the recent application of miniaturized versions of clinical imaging tools such as PET scanning and MRI, confocal and especially multiphoton microscopy, and luminescence imaging to living animals, permitting direct spatiotemporal analysis of immune cells within complex tissue environments. However, standards for data analysis and interpretation are just emerging, as are improved methods that bridge the resolution and time gaps between the various methods, allowing analyses to begin with initiation of a response and to follow it through to pathogen/tumor clearance or induction of autoimmune pathology. This meeting will bring together experts who will describe ongoing and future applications of these new imaging methods and provide the attendees with an understanding of the new biological paradigms that are emerging from such investigations. Speakers will discuss both basic and clinically-related advances, including cell-cell interactions in the development of humoral and cell-mediated immune responses, the events underlying autoimmune pathology in models of rheumatoid arthritis and diabetes, the trafficking of hematopoietic stem cells following grafting, signaling events in the thymus, bone marrow, and secondary lymphoid tissues, the sites of Treg activity, and the interplay between tumor cell growth and immune cell effector activity following anti-cancer vaccination.
 
 
Organized by: Ronald N. Germain and Ellen A. Robey
Invited Speakers: - Philipe Bousso, Institute Pasteur
- Doreen Cantrell, University of Dundee
- Jason Cyster, University of California, San Francisco
- Mark Davis, Stanford University
- Michael Dustin, New York University School of Medicine
- Scott Fraser, California Institute of Technology
- Ronald Germain, NIAID, National Institutes of Health
- Chien Ho, Carnegie Mellon University
- Robert Hoffman, AntiCancer, Inc.
- Marc Jenkins, University of Minnesota
- John Kehrl, NIAID, National Institutes of Health
- Matthew Krummel, University of California, San Francisco
- Richard Lewis , Stanford University
- Philippa Marrack, National Jewish Medical and Research Center
- Diane Mathis, Harvard Medical School
- Mark Miller, Washington University School of Medicine
- Michel Nussenzweig, Rockefeller University
- David Piwnica-Worms, Washington University School of Medicine
- Ellen Robey, University of California, Berkeley
- Ulrich Von Andrian, Harvard Medical School
 
Deadline for Abstracts: Oct. 25, 2006
 
Registration: Please see website
E-mail: info@keystonesymposia.org
 
   
 
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