GTCBIO, Silver Spring
April 6-7, 2006
DAY 1 Thursday, April 6, 2006
7:00
Registration & Breakfast
8:00
Opening Remarks/Conference Goals
CONFERENCE CHAIR: Richard Margolin, M.D.,
Senior Director, CNS (North America), i3Research
Visiting Scholar, Laboratory of Molecular Imaging,
David Geffen School of Medicine, UCLA
8:15 KEYNOTE PRESENTATION:
Henry N. Wagner, Jr., M.D., Visiting Professor of Radiology, Director, Division of Nuclear Medicine, Vice Chairman for Technology and Business Development, Johns Hopkins Medical Institutions
9:00 TBA
Barbara Y. Croft, Ph.D., Cancer Imaging Program, National Cancer Institute
SESSION 1 - MODALITIES
9:30
Small Animal Optical Imaging Umar Mahmood, M.D., Ph.D., Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School
10:00
30 MINUTE BREAK
10:30
The Role of PET in Drug Discovery with Focus on P-glycoprotein Functionality Philip Elsinga, University Medical Center Groningen
11:00
Imaging the Esophagogastric Transit of Pharmaceutical Dosage Forms
Alan Perkins, PhD , FIPEM, ARCP, University Hospital of Nottingham
11:30
Oral Presentations from Selected Abstracts: In Vivo Assessment of Myocardial Function in Spironolactone Treated Insulin Resistant Rats via Cine Magnetic Resonance Imaging (MRI) Shawna Cooper, Sr. Research Specialist, Department of Internal Medicine-ENDO Sowers Lab, Harry S. Truman Veteran's Hospital Imaging of Cancer-Induced Bone Destruction using Micro Computed Tomography Andreas Evdokiou, The University of Adelaide
12:00
LUNCH
SESSION 2 – APPLICATIONS IN ONCOLOGY & CARDIOLOGY
1:30
Imaging Science and Oncologic Drug Development G.J. Kelloff, National Cancer Institute
2:00
Optical Tomographic Small Animal Imaging System to Monitor Tumor Growth and Regression
Andreas H. Hielscher, Ph.D., Associate Professor Departments of Biomedical Engineering & Radiology, Columbia University
2:30
Non-invasive Bioluminescence Imaging of Spontaneous Tumorigenesis and Angiogenesis in Mice Scott K. Lyons, Xenogen
3:00
In Vivo Monitoring of Human Embryonic Stem Cell-derived Graft Function in Living Animals using Optical Bioluminescence Imaging Technologies
Michelle Bradbury, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center
3:30
Refreshment Break
4:00
Tumor Imaging with Small Molecule Inhibitors Padmaja Yalamanchili, Ph.D.,Bristol Myers Squibb Medical Imaging
4:30
Atheroma: Developments in Imaging Surrogates of Risk Jonathan Gillard, BSc MD FRCR, University of Cambridge
5:00 KEYNOTE PRESENTATION:
Strategic Role of Imaging in Drug Development: Structure and Function
Helen Young, Ph.D., AstraZeneca
5:45
NETWORKING RECEPTION
DAY 2 Friday, April 7, 2006
7:00
Registration & Breakfast
SESSION 3– APPLICATIONS IN CNS
8:00 The Preclinical Development of CNS PET Radiotracers Shailendra Patel, Ph.D., Merck
8:30 The Development of Amyloid Specific Imaging Agents for Application in Alzheimer's Disease Andrew Lockhart, Ph.D., Neurology Biomarker Group, TMG, GlaxoSmithKline
9:00 PET Imaging of Amyloid Deposition using Pittsburgh Compound-B
Julie Price, University of Pittsburgh
9:30 Refreshment Break
10:00 In Vivo Drug Effects on Dopaminergic System Bruce Jenkins, Ph.D., Instructor in Radiology, Director of Neurochemical Imaging
Department of Radiology, MGH, Harvard Medical School
10:30 Imaging Techonology: Applications in CNS Richard Margolin, M.D., UCLA & i3Research
SESSION 4 – BIOMARKERS
11:00 Imaging Biomarkers in Drug Development: An Overview of Opportunities and Open Issues Mac Johnson, Millennium Pharmaceuticals
11:30 Unique Challenges in the Discovery of Novel Imaging Agents: What is an Image-able Biomarker? Michael Montalto, Ph.D., GE Global Research
12:00 LUNCH
SESSION 5 – CHALLENGES & OPPORTUNITIES
1:30 Utilizing Functional & Molecular Imaging Techniques Thomas Zeffiro, M.D., Ph.D., Director, GU Center for Functional and Molecular Imaging, Georgetown University
2:00 Challenges and Opportunities for Positron-emission Tomography in Personalized Medicine Suzanne V. Smith, Ph.D., Australian Nuclear Science & Technology Organization
2:30 Using Functional Magnetic Resonance Imaging in Awake Mice
Gerard B Fox, Ph.D., Project Leader, Global Pharmaceutical Discovery,
Abbott Laboratories
3:00 Refreshment Break
3:15 Commercialization of Research Tools
Richard Smith, Edwards Angell Palmer & Dodge
3:45 How Can Imaging Reshape Clinical Research by Accelerating Medical Discovery? William C. Eckelman, Ph.D. Chief Scientific Officer, Molecular Tracer, LLC
4:15 CONFERENCE CONCLUDES
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