British Neuropathological Society, University of London, Wye College, Kent UK
6-9 July 2004
Protein aggregation diseases - Chair: J Lowe
What are aggresomes and why are aggregates found in different cellular compartments? - R Kopito
How are proteins that aggregate eliminated from neurones: Polyglutamine expansion proteins - D Rubinstein
Mechanisms of intracellular protein degradation - RJ Mayer
How are protein aggregates eliminated from the cell: tau and synuclein - R Layfield
Central motor systems: Chair: P Shaw
Neurofilament function, axons and motor system diseass - C Miller
Cytoskeletal and mitochondrial function in hereditary spastic paraparesis - P Shaw
Genetics and pathogenesis of the spinal muscular atrophies - M Sendtner
New neurodegenerative disorders Chair: P Ince
Inherited amyloidoses (familial British & Danish dementias) - T Revesz
Neuroferritinopathy - C Morris
Lipid rafts and signalling - Chair: S Love
GDNF family neurotrophic factor signalling and lipid rafts - M Saarma
Title to be confirmed - M Schachner
Lipid rafts and glial cell signalling - EM Krämer
Amyloid processing: the role of cholesterol - C Dingwall
Role of lipid rafts in the processing of Alzheimer’s and prion proteins - N Hooper
Stem cells & neural precursors - Chair: W Blakemore
The potential of ES cells - S Chandran
Is multiple sclerosis a candidate for stem cell therapy? - W Blakemore
Bone marrow stem cells - M Alison
Delegate presentations
Neuromuscular disorders - Chair: D Hilton
Disorders of fatty acid oxidation and neuromuscular disease - S Olpin
Mitochondrial disease - A Schapira
Update on limb girdle muscular dystrophy - L Anderson
Glycosylation defects in neuromuscular disease - F Muntoni
Pharmacotherapeutics - Chair: S Love
Neurotrauma and head injury treatment problems - J Pickard
Small molecule therapeutics: In Silico design or high resolution screening? - SJ Allen
Pharmacogenetics of neurological disease - R Gibson
BACE inhibitor development - I Hussain
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