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Elsevier, New Orleans, USA
November 6 - 7, 2003
Oral programWEDNESDAY NOVEMBER 5, 2003
18:00-20:00 Conference registration
THURSDAY NOVEMBER 6, 2003
07.30 Conference registration
09.00 Introduction
Caleb Finch, University of Southern California, CA, USA
Paul D. Coleman, University of Rochester Medical Center, NY, USA
09.45 COFFEE
Session 1: Early Predictors (PART I)
10.15 Mid-life risk factors for late-life dementia: lessons from epidemiologic studies
Leonore J. Launer, National Institute on Aging, MD, USA
10.55 Presentation title and speaker to be confirmed
11.35 Early life factors, mild cognitive impairment, and the neuropathology of Alzheimer's disease: Findings from the Nun Study
Kathryn P. Riley, University of Kentucky, KY, USA
12.15 LUNCH
Session 2: Early Predictors (PART II)
13.45 Atherosclerosis: development, progression and complications - insights from intravascular ultrasound
E. Murat Tuzcu, Cleveland Clinic Foundation, OH, USA
14.25 Developmental and vascular risk factors for Alzheimer's disease (provisional)
Amy Borenstein, University of South Florida, FL, USA
15.05 COFFEE
Session 3: ApoE Effects (PART I)
15.35 Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease
Judes Poirier, McGill University, Canada
16.15 Cardiovascular risk factors in youth with implications for aging: the Bogalusa Heart Study
Gerald S. Berenson, Tulane University, LA, USA
16.55 Presentation title and speaker to be confirmed
17.35 - 17.50 Summary of first day
Caleb Finch and Paul D. Coleman
18.00 POSTER SESSION
18.30-19.30 DRINKS RECEPTION
FRIDAY NOVEMBER 7, 2003
Session 4: ApoE Effects (PART II)
09.00 Cardiovascular functional phenotypes and pathological changes in response to pharmacological stimulation of Apolipoprotein E deficient mice
Yi-Xin Wang, Berlex Laboratories, CA, USA
09.40 Sex, ApoE and the innate immune response
Carol A. Colton, Duke University Medical Center, NC ,USA
10.20 COFFEE
10.50 ApoE binding to specific cell surface receptors activates unique cell signaling pathways that result in inhibition of cell migration and proliferation
David Hui, University of Cincinnati, OH, USA
11.30 PET in the study of aging and the genetic predisposition to Alzheimer's disease
Eric M. Reiman, University of Arizona, AZ, USA
12.10 LUNCH
Session 5: Early Changes in the Down Model
13.30 Development and dementia in Down Syndrome: implications for Alzheimer's disease
Ira T. Lott, University of California at Irvine, CA, USA
14.10 Genetic influences on proteolysis in aging and aging-related neurodegenerative disease
Ralph Nixon, Nathan Kline Institute for Psychiatric Research, NY, USA
14.50 Cytokines, aging and neurodegenerative disease
Sue T. Griffin, University of Arkansas Medical Sciences,AR, USA
15.30 COFFEE
Session 6: Panel Discussion
16.00 Panel discussion
Carol A. Colton, Duke University Medical Center, NC, USA
Caleb Finch, University of Southern California, CA, USA
Marcelle Morrison-Bogorad, National Institute on Aging, MD, USA
Ronald B. DeMattos, Lilly Research Laboratories, IN, USA
17.00 Concluding remarks
Caleb Finch and Paul D. Coleman
17.15 CLOSE OF CONFERENCE
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