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Elsevier, New Orleans, USA
November 5 - 7, 2003
Wednesday November 5, 2003
12.30 Conference Registration
14.00 Opening Remarks
Stephen J Moss, University of Pennsylvania, PA, USA
Richard L Huganir, Johns Hopkins University School
of Medicine, MD, USA
14.10 Dopaminergic signalling
Paul Greengard, Rockefeller University, NY, USA
TARGETING SIGNALING COMPLEXES TO ION CHANNELS
Chair: Stephen J Moss, University of Pennsylvania,
PA, USA
14.50 Regulatory protein complexes associated with
neuronal potassium channels
Irwin B Levitan, University of Pennsylvania, PA, USA
15.25 The molecular architecture of kinase phosphatase
signaling complexes
John D Scott, Oregon Health & Sciences University,
OR, USA
16.00 Refreshments
16.30 Monoaminergic modulation of neuronal excitability
D James Surmeier, Northwestern University Medical
School, IL, USA
17.05 Poster Session One and Drinks Reception
19.05 End of Day OneThursday November 6, 2003
FACILITATING THE ACTIVITY OF NEUROTRANSMITTER
RECEPTORS AND TRANSPORTERS; THE ROLES OF
PHOSPHORYLATION AND MEMBRANE TRAFFICKING.
Chair: Richard L Huganir, Johns Hopkins University
School of Medicine, MD, USA
09.00 Tyrosine kinase/phosphatase modulation of NMDA
receptors in synaptic signalling and plasticity
Michael W Salter, Hospital for Sick Children,
Toronto, Canada
09.35 Regulation of NMDA receptor trafficking
Katherine W Roche, NIH, MD, USA
10.10 GABA-A receptors dancing with multiple
signalling partners
Jasmina Jovanovic, University College London, UK
10:45 Refreshments
11.15 Organization of signaling pathways at
postsynaptic sites
Johannes Hell, University of Iowa, IA, USA
11.50 Regulation of G protein-coupled receptors by
membrane trafficking
Mark Von Zastrow, UCSF, CA, USA
12.25 Regulation of synaptic function by monoamine
transporters
Marc Caron, Duke University Medical Center, NC,
USA
13.00 Lunch
UBIQUITINATION: AN EMERGING MECHANISM FOR
REGULATING SYNAPTIC SIGNALING
Chair: Graham Collingridge, University of Bristol, UK
14.00 Secretory systems serving the synapse
Michael D Ehlers, Duke University Medical Center,
NC, USA
14.35 Regulation of seven-membrane spanning receptor
trafficking by ubiquitination
Sudha Shenoy, Duke University Medical Centre, NC,
USA
15:10 Role of ubiquitin in regulating synaptic
transmission in C. elegans
Joshua M Kaplan, Massachusetts General Hospital,
MA, USA
15.45 Refreshments
16.15 Submitted Oral Presentations
17.45 Poster Session Two
19.15 End of Day Two Friday November 7, 2003
REGULATING PRESYNAPTIC ACTIVITY
Chair: Irwin B Levitan, University of Pennsylvania, PA, USA
09.00 Regulation of neurotransmitter release by calcium
channels and calcium sensors
Thomas Sudhof, University of Texas, TX, USA
09.35 Phosphoinositide metabolism in presynaptic function
Pietro V De Camilli, Yale University, CT, USA
10.10 Actin dynamics and modulating neurotransmitter
release
Yukiko Goda, University College London, UK
10.45 Refreshments
11.15 How voltage-gated Ca2+ channels autoregulate
themselves
Richard W Tsien, Stanford University, CA, USA
11.50 The role of calcium channel beta subunits in
calcium channel modulation by G proteins and
protein kinases
Annette Dolphin, University College London, UK
12.25 Regulation of neurite outgrowth and growth cone
motility by CaM-kinases
Thomas Soderling, Oregon Health Science
University, OR, USA
13:00 Lunch
MODIFIED ION CHANNEL ACTIVITY AS A BASIS FOR
SYNAPTIC PLASTICITY
Chair: Richard W Tsien, Stanford University, CA, USA
14.00 Role of phosphorylation in hippocampal LTP and
LTD
Graham Collingridge, University of Bristol, UK
14.35 Phosphorylation of AMPA receptors and the
expression of synaptic plasticity
Richard L Huganir, Johns Hopkins University School
of Medicine, MD, USA
15.10 Cerebellar long-term synaptic potentiation:
cellular and molecular mechanisms
David Linden, Johns Hopkins University School of
Medicine, MD, USA
15.45 Refreshments
16.15 Synaptic plasticity regulated by stargazin and
PSD-95
David Bredt, UCSF, CA, USA
16.50 Immediate early genes and synaptic function
Paul Worley, Johns Hopkins University School of
Medicine, MD, USA
17.25 Closing Remarks
17.30 End of Conference
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