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  Translational Research in Autoimmunity  
  October 01, 2002

Others

 
     
  Istituto Giannina Gaslini, Hotel Portofino Kulm, Portofino (Genoa), Italy
April 3 - 6, 2003


1) Tools and Strategies for Translational Research

- Autoimmune disease: why and where it occurs
- From bench to bedside
- International networks for rare diseases
- The evolution of the biotech industry
- The NIH model of support for translational research
- EU strategies for translational research
- Safety vs. Speed: the FDA perspective to regulatory issues

2) T Cell Mediated Intervention

- The immune synapse as a target of intervention
- Molecular determinants of epitope immunogenicity
- Definitions and modulation of the T cell repertoire by altered peptide ligands
- Animal models of antigen specific immune modulation
- Heat shock proteins as immunemodulators in animal models
- Heat shock proteins as tools of intervention in autoimmunity
- Suppressor T cells
- Regulatory T cells

3) Antigen-Specific Intervention

- Modulation of antigen specific T cell responses in rheumatoid arthritis
- Immunoregulation in the therapy of autoimmune diabetes
- Immune modulation in multiple sclerosis
- Antigen specific therapy of diabetes

4) Antigen presenting cells, Soluble and Accessory Molecules as Tools for Intervention

- Antigen presenting cells as tools for immune therapy
- Role of the epithelium in orchestrating the onset of innate and acquired immune responses
- Control of autoaggression and tumor immunity by the microenvironment
- Dendritic cells as targets for immune intervention
- Anergy and apoptosis in immune tolerance and autoimmunity
- Current experience with intervention on CD40
- Natural killer cells as effectors and regulators
- Modulation of cytokine profiles
- Perspectives of anti-IL-6 therapy
- Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines
- Chemokines and chemokine receptors
 
 
Organized by: Istituto Giannina Gaslini
Invited Speakers: B Kotzin (Denver)
D Carson (San Diego)
A Martini (Genova)
S Fumero (Milano)
S Sztein (Bethesda)
J Siegel (Washington)
A Lanzavecchia (Bellinzona)
A Sette (San Diego)
E Sercarz (San Diego)
V Kuchroo (Boston)
W van Eden (Utrecht)
B Prakken (Utrecht)
J Bluestone (San Francisco)
MG Roncarolo (Milano)
S Albani (San Diego)
JF Bach (Paris)
D Hafler (Boston)
I Cohen (Rehovot)
R Steinman (New York)
M Kagnoff (San Diego)
G Hammerling (Heidelberg)
L Adorini (Milano)
A Abbas (San Francisco)
B Lipsky (Bethesda)
L Moretta (Genova)
S Romagnani (Firenze)
F De Benedetti (Roma)
A Manotovani (Milano)
F Sinigaglia (Milano)
 
Deadline for Abstracts: 15 February 2003
 
Registration: Registration deadline: March 14, 2003

Registration fees:

Full
< March 14, 2003 300.00 €
> March 14, 2003 400.00 €

Students(under 36 years of age)
< March 14, 2003 150.00 €
> March 14, 2003 200.00 €
E-mail: sisp@ospedale-gaslini.ge.it
 
  Posted by:   Thomas Wiley  
Host: 62.101.86.84
   
 
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