HUM-MOLGEN events: CHI's PROTEIN ARRAYS

HUM-MOLGEN -> Events -> Meetings and Conferences

September 21, 2001

Cambridge Healthtech Institute, Hilton San Diego Resort, San Diego, California
January 7-8, 2002

Microarrays have revolutionized genomic studies. Protein arrays have the same potential to impact proteomics. Protein arrays can be used to screen for interaction of proteins with other proteins, DNA, antibodies, cells, or small molecules. The two major formats designed to serve rather different applications present different technical challenges and opportunities. Immobilization of numerous proteins requires efficient protein expression and strategies that retain activity. Determination and quantification of protein expression levels require arrays designed to selectively capture proteins in solution. Numerous technical obstacles, such as optimizing protein immobilization or selection of protein-binding ligands, strategies for extending the limits of detection, and novel applications of this exciting technology, are among the issues that will be discussed in detail.

Organized by:

Cambridge Healthtech Institute

Invited Speakers:

SYSTEMS
Probing the Proteome: The Development of Protein Biochips
Dr. Lawrence K. Cohen, Zyomyx, Inc
SELDI ProteinChip® Technology: Phenotyping by Pattern Recognition
Dr. Enrique A. Dalmasso, Ciphergen Biosystems, Inc.
Global Analysis of the Biochemical Activities Using Proteome Chips
Dr. Metin Bilgin, Yale University

APPLICATIONS
Cancer Serum Diagnostics Using Protein Microarrays
Dr. Brian B. Haab, The Van Andel Institute
Activity-Based Protein Profiling: Chemical Approaches for Functional Proteomics
Dr. Benjamin F. Cravatt, The Scripps Research Institute

BINDING
ProteinPrint: A Novel Sequence-Based Protein Separation Technology for Predictable Proteomics
Dr. Casey Lynch, Aspira Biosystems, Inc.
Development of an Automated Directed Protein Evolution Engine to Produce High-Affinity Binders for Protein Microarrays
Dr. Richard W. Wagner, Phylos, Inc.
Advances in the Development of Protein Microarrays Utilizing Novel Synthetic Affinity Binding Surfaces
Dr. Karin A. Hughes, Prolinx Inc.
Protein in Situ Arrays (PISA): Single-Step Generation of Protein Arrays from DNA by Cell-Free Expression
Dr. Michael Taussig, The Babraham Institute

DETECTION
FLEX CHIP™ Kinetic Analysis System: A Surface Plasmon Resonance Imaging Platform for Rapid, Label-Free, Array-Based Sensing in Proteomics Research
Dr. Jennifer M. Brockman, HTS Biosystems, Inc.
Protein Analysis in an Array Format Using a Novel, Highly Sensitive Detection System: Resonance Light-Scattering Particles
Dr. Heather Pancio, Incyte Genomics, Inc.
Mass Spectrometry and Protein Arrays: Design and Applications of Mass Spectrometric Immunoassay and Biomolecular Interaction Analysis Mass Spectrometry in Protein Analysis
Dr. Dobrin Nedelkov, Intrinsic Bioprobes Inc.

Deadline for Abstracts:

December 7, 2001

Registration:

http://www.chi-peptalk.com/reg.htm

E-mail:

fvargus@healthtech.com

Posted by:

Frederick Vargus

Host:

wks253.healthtech.com