HUM-MOLGEN events: CHEMICAL GENOMICS/ CHEMOGENOMICS

HUM-MOLGEN -> Events -> Meetings and Conferences

July 26, 2001

Cambridge Heathtech Institute, Boston, Massachusetts
November 16, 2001

Chemical Genetics describes the use of small synthetic molecules, which elicit a phenotypic change by direct protein interaction, to identify key genes involved in the specific biological pathway of interest. In many cases existing drugs are used as the chemical probes whose overall effect is well established but whose mode of action is not well understood. Chemical genetic experiments, therefore, present an opportunity to clarify the specific mode of action of well-known therapeutics. The current wealth of gene sequence information available, in conjunction with recent advances in array-based technologies, has facilitated a chemical genomic approach. High-throughput screening with small, highly specific, synthetic molecules, against multiple protein targets, results in measurable phenotypic changes and presents an opportunity to do gene functional analysis and create new therapeutic leads at the same time. Chemogenomic drug discovery is an emerging new field in which small molecule leads, identified for one member of a gene family, are used to elucidate the function and biological role of another member of that family whose function is not known, as well as to identify potential drug leads. Both Chemical Genomics and Chemogenomics represent newer approaches to target identification and drug development with the potential for dramatically accelerating the process. Anyone interested in such prospects should attend this conference.

Organized by:

CHI

Invited Speakers:

Dr. Stuart L. Schreiber, Harvard University
Dr. Brent R. Stockwell, Whitehead Institute for Biomedical Research
Dr. Satish Jindal, Neogenesis, Inc.
Dr. Kevin Koch, Array BioPharma
Dr. Min Li, Johns Hopkins University School of Medicine
Dr. Michael McPherson, Phylos, Inc.
Dr. Donald G. Payan, Rigel, Inc.
Dr. Scott Selleck, Arizona Cancer Center
Dr. Mark Velleca, Cellular Genomics Inc.
Dr. X.F. Steven Zheng, Washington University School of Medicine

Deadline for Abstracts:

October 19, 2001

Registration:

Available on-site

E-mail:

jlaakso@healthtech.com

Posted by:

Jennifer Laakso

Host:

wks217.healthtech.com