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  HIGH-THROUGHPUT ORGANIC SYNTHESIS  
  December 05, 2000

Biotechnology

 
     
  Cambridge Healthtech Institute, San Diego, California
February 14-16, 2001


Combichem programs face the challenge of meeting the demand of HTS for growing numbers of compounds, while still meeting the critical criteria of more novel chemistries and structures, less overlap with existing libraries, more druglike properties, greater purity, and lower cost. These factors play an important role as HTS speeds rise and as the number of genomically derived targets explode. New resins and linkers offer easier, faster, and more practical synthetic methodologies for compound synthesis in manual, semiautomated, and automated approaches increasing the synthesis throughput as well as compound purity. Novel chemistries and reaction strategies, particularly for building blocks, will be key to extending the range of diversity produced, while still keeping costs low. Increased demand for compound/library purity and more rigorous QC demands high-throughput purification protocols impacting the turnaround compound/library production timeframe with the benefit of generating reliable screening data feedback for lead follow-up. This conference will provide you with plenty of new information about the details of combinatorial and parallel synthesis, so plan to attend.

 
 
Organized by: Cambridge Healthtech Institute
Invited Speakers: Dr. Rhett Affleck, IRORI (a Discovery Partners International Company)
Dr. David J. Austin, Yale University
Dr. Armen M. Boldi, ChemRx Advanced Technologies, Inc.
(a Discovery Partners International Company)
Dr. Kevin Burgess, Texas A & M University
Dr. Huw M.L. Davies, State University of New York at Buffalo
Dr. Dale S. Dhanoa, PharmaCore, Inc.
Dr. M. G. Finn, The Scripps Research Institute
Dr. Michael Griffith, Trega Biosciences, Inc.
Dr. Vijay Gupta, Personal Chemistry AB, Sweden
Dr. Normand Hébert, Trega Biosciences, Inc.
Dr. C. Oliver Kappe, Karl-Franzens-University Graz
Dr. Kyungjin Kim, Hoffmann-La Roche, Inc.
Dr. Kevin Koch, Array BioPharma
Dr. Boliang Lou, Advanced SynTech, LLC
Dr. Aubrey J. Mendonca, Polymer Laboratories Inc.
Dr. Michael Moore, SmithKline Beecham Pharmaceuticals
Dr. Ben Moshiri, Mettler-Toledo Bohdan, Inc.
Dr. Jan J. Scicinski, GlaxoWellcome
Dr. Joan M. Stevens, Gilson, Inc.
Dr. Irving Sucholeiki, Solid Phase Sciences Corporation
Dr. Werner Zinsser, Zinsser Analytic, Inc.
 
Deadline for Abstracts: January 5, 2001
 
Registration: Available on-line
E-mail: jlaakso@healthtech.com
 
  Posted by:   Jennifer Laakso  
Host: wks217.healthtech.com
   
 
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