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HUM-MOLGEN events
Towards New Diagnostic and Therapeutic Concepts
 
German Society of Experimental and Clinical Pharmacology and Toxicology and Sixth International Dahlem Symposium on "Cellular Signal Recognition and Transduction" , Berlin, Germany
September 27 - 30, 2000


PRELIMINARY PROGRAM
(as at July 18, 2000)

The program is also available as pdffile.

Wednesday, September 27, 2000

12:00 - 18:00 Registration, put up posters (Henry-Ford-Bau)

19:00

OPENING (location to be announced)
Welcome addresses:
Peter Gaehtgens, President of the Freie Universität Berlin
Kay Brune, President of the DGPT

Opening Lecture:
Burghardt Wittig (Berlin)
Speculation and hype versus data and hope: Will the markets cure molecular medicine's sickness

RECEPTION


Thursday, September 28, 2000

08:00

Registration, put up posters

INTRACELLULAR RECEPTORS

Chair:

Wolf-Dieter Schleuning (Berlin)

09:00

Steven A. Kliewer (Research Triangle Park):
Nuclear receptors in molecular toxicology

09:30

Martin Göttlicher (Karlsruhe):
Ah (dioxin) receptor and hypoxia inducible factors (HIFs) in the cellular response to environmental conditions

10:00

William Bourguet (Strasbourg):
The retinoid and rexinoid systems: Structural basis of ligand action, novel RXR signalling pathways, and molecular basis of retinoid-induced apoptosis

10:30

Holger M. Reichardt (Heidelberg)
Glucocorticoid and mineralocorticoid receptors

11:00

Break

G-PROTEIN-COUPLED RECEPTORS

Chair:

Micheal Freissmuth (Vienna)

11:30

Bernhard Bettler (Basel):
GABAB receptors - the first G-protein coupled hetero-dimers

12:00

Marc Parmentier (Brussels):
Chemokine receptors and HIV coreceptors

12:30

Mark von Zastrow (San Francisco):
Novel protein interactions of G-protein coupled receptors

13:00

Break

14:30

Henry M. Sarau (King of Prussia):
Urotensin receptors

15:00

Olivier Civelli (Irvine):
Orphan G-protein coupled receptors and their ligands

ADHESION RECEPTORS

Chair:

Walter Birchmeier (Berlin)

15:30

Martin Lipp (Berlin):
Functional organization of the immune response by homeostatic chemokines

16:00

Break

16:30

Nancy Hogg (London):
Integrin activation and the consequences

17:00

Ernst Theodor Rietschel (Borstel):
Bacterial inducers of inflammation

17:30

Beat Imhof (Geneva):

18:00

Break

19:00

Special Lecture:
Franz Hofmann
(München):
New ion channel families


Friday, September 29, 2000

STRUCTURAL BASIS OF PHARMACOLOGY

Chair:

Klaus Aktories (Freiburg)

08:30

Per Bork (Heidelberg):
Prediction of structure and function

09:00

Günther Jung (Tübingen):
Potentials of combinatorial peptide chemistry in autoimmune research

09:30

Christian Griesinger (Frankfurt/M.):
Advances in NMR technology

10:00

Hartmut Oschkinat (Berlin):
Studying protein peptide interactions by NMR

10:30

Break

11:00

Anthony Watts (Oxford):
Resolving structural details of membrane-embedded targets and receptors using solid state NMR

11:30

Horst Kessler (Garching):
From protein to drugs - Rational design and combinatorial approaches for the development of selective integrin-antagonists

12:00

Fred Wittinghofer (Dortmund):
The Ras oncogene as an anti-tumor target

12:30

Break

14:15

Special Lecture:
Stephen Sprang
(Dallas):
Crystal structure of G proteins and adenylyl cyclases

TRANSGENIC ANIMALS

Chair:

Franz Hofmann (München)

15:00

Rudolf Balling (München):
From sequencing nucleotides to sequencing pathways: A large scale ENU mutagenesis screen in mice

15:30

Uwe Rudolph (Zürich):
Benzodiazepine actions mediated by specific GABAA receptor subtypes

16:00

Rolf Sprengel (Heidelberg):
AMPA receptor mediated synaptic plasticity in the hippocampus of GluR-A subunit deficient mice

16:30

Break

17:00

Shu Narumiya (Kyoto):
Physiological and pathophysiological roles of prostanoids; lessons from receptor-knockout mice

17:30

Lutz Hein (Würzburg):
Gene-targeting in mice reveals distinct functions of three alpha2-adrenergic receptor subtypes

18:00

Jeffery D. Molkentin (Cincinnati):
Transgenic manipulation of phosphotases in the mouse heart: implications for cardiac hypertrophic signaling

20:30

Banquet


Saturday, September 30, 2000

09:00

Special Lecture:
Hermann Bujard
(Heidelberg)
How to achieve temporal and spatial control of gene activities in transgenic animals

PHARMACOGENOMICS/PHARMACOGENETICS

Chair:

Ivar Roots (Berlin)

09:45

Herbert Schuster (Berlin):
Pharmacogenetics of lipid disorders

10:15

Patrizia T Ferrari (Milan):
Pharmacogenomics of essential hypertension

10:45

Mark J. Rieder (Seattle):
DNA Variation, Haplotypes and the Renin-Angiotensin-System

11:15

Break

11:45

Klaus Lindpaintner (Basel):
Pharmacogenomics and the pharmaceutical industry

12:15

Stefan Schulte-Merker (Tübingen):
The zebrafish as a pharmacogenomic model

12:45

Günther Heinrich (Bernried):
Pharmacogenomics: Its role in drug developement and therapy

13:15

Closing ceremony

 

 

NOTE: The program is subject to change.


Organized by:

German Society of Experimental and Clinical Pharmacology and Toxicology and Sixth International Dahlem Symposium on "Cellular Signal Recognition and Transduction"

Invited Speakers:

see programm

Deadline for Abstracts:

July 28, 2000

Registration:

You can either print the registration form and send it to the congress office or fill in the online form.
Email for Requests and Registration: paul@medizin.fu-berlin.de
 
 

Posted by: FS Zollmann   Host: squid.fu-berlin.de
date: July 20, 2000 13:06:29
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