Application of Genomics to ANIMAL MODELS for Pharmaceutical Studies
	Cambridge Healthtech Institute , Boston, Massachusetts November 15-16, 2000
	With the ongoing sequencing of the genomes of several animal species ranging from Drosophila and zebra fish to rats and mice, their simpler genomes have given researchers a tool for exploring gene function as applied to the more extensive and complex human genome. The use of genetically engineered rats and mice to explore the function of genes and for the selection of appropriate drug targets holds great promise in speeding the development of valuable therapies. These models provide effective ways to test new drug compounds, as well as aid in our understanding of specific disease processes. This conference will explore the efficient production of these and other more simple models, as well as the use of various animal models to carry out more rapid and cost-effective pharmaceutical studies.
	Organized by:	Cambridge Healthtech Institute
	Invited Speakers:	A Simple and Efficient Method to Prepare Genetically Engineered Animals Dr. Jaspal S. Khillan, University of Pennsylvania DNA-Based Techniques for the Determination of Carrier Status, Zygosity, and Background Strain Identity in Transgenic and Knockout Rodents Mr. William F. Gergits, Charles River Laboratories Genetic Background of Inbred Strains: Basis for Accelerated Backcrossing Dr. Gerald W. M. Bothe, Taconic Biotechnology Integrating Molecular Genetic Information into a Biogenic Model to Enhance the Selection Process Dr. H. T. Blair, Massey University (New Zealand) Zebra Fish: A Vertebrate Model for Target Discovery and Functional Validation Dr. Stefan Schulte-Merker, Artemis Pharmaceuticals GmbH (Germany)Genetic Alterations in Natriuretic Peptide Receptor-A: Novel Target for Hypertension and Cardiovascular Disease States Dr. Kailash A. Pandey, Tulane University School of Medicine A Reversible Model of Huntington’s Disease Dr. Ai Yamamoto, Columbia University Aging Pathway Associated with Important Human Tumor Suppresser Gene Dr. James Piggott, Lexicon Genetics, Incorporated Genetic Breeding Experiments to Identify Specific Role of Terminal Complement in the Immune System: A Case Study Dr. Louis Matis, Alexion Pharmaceuticals (invited) Identifying Genes for Long-Term Survival of Human Tuberculosis in a Frog Model Dr. Stanley Falkow, Stanford University (invited)
	Deadline for Abstracts:	October 13, 2000
	Registration:	Available on-line
	Email for Requests and Registration:	jlaakso@healthtech.com
	Posted by: Jennifer Laakso   Host: wks217.healthtech.com date: June 29, 2000 17:32:52 Generated by meetings and positions 2.0 by Kai Garlipp Logo and Logo Images by Art for BioMed / Syrinx GmbH - Frankfurt / Germany. 4.1 (c) 1995-99 HUM-MOLGEN. All rights reserved. Liability and Copyright.