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PERSPECTIVES on PROTEIN ENGINEERING: Discovery, Design & Development of Pharmaceutical & Industrial Proteins

John Innes Centre , John Innes Centre, Norwich, Norfolk, UK
28 Jone - 1 July 1997

Invited Speakers: J Craig Venter (TIGR, USA) Genome Characterization: from Man to MicrobesAmos Bairoch (Geneva, Switzerland) SWISS-Prot today & tomorrowMike Bevan (JI Centre, Norwich) Progress in plant genomesDave Roberts (London) The contribution of taxonomyIain Campbell (Oxford. UK) Design & evolution of protein domainsRik Wierenga (EMBL, Heidelberg, Germany) Redesigning protein loopsShuguang Zhang (MIT, Boston, USA ) Designing new biomaterialsMarius Clore (NIH, USA) Structures of protein-DNA complexes in solution: the chromatin remodeling factor GAGA and the transcription modulator HMG-I/Y.Peter Leadlay (Cambridge) Tailoring antibiotics by pathway engineeringPeter Laing (Peptide Therapeutics) Generation of Pharmacophoric Models of Biomolecules Using Information from Library-Derived PeptidesJose Marcos (Barcelona, Spain) Achieving plant pathogen resistance through combinatorial chemistryPoster sessionJohn MaCafferty (CAT, Cambridge) Isolation of antibodies to cell surface from phage display repertoires.Udo Conrad (Gatesleben, Germany) Antibody expression in plantsDenis Murphy ( JI Centre, Norwich) Use of Engineered Proteins in Molecular PharmingGeorge Lomonossoff (JI Centre, Norwich) Human vaccine production in plantsTransgenic Farm Animal Production (TBA)Chris Schofield (Oxford, UK) Dioxygenases Richard Pickersgill (IFR Reading) Papaya proteasesGeoff Fincher (Adelaide, Australia) Beta-glucanasesBirte Svensson (Valby, Denmark) AmylasesMike Williamson (Sheffield, UK) Starch recognition by a starch-binding domain from glucoamylasesL Mario Amzel (Johns Hopkins, USA) LipoxygenasesJohn Rafferty (Sheffield, UK) Fatty acid synthetasesDidier Marion (Nantes, France) Lipid binding proteinsMike Lawrence (Parkeville, Australia) 7S/11S GlobulinsPeter Shewry (Long Ashton, UK) Structure & action of glutens

6th International Conference PERSPECTIVES ON PROTEIN ENGINEERINGDiscovery, Design and Development of Pharmaceutical and Industrial Proteins: the Challenges for Structural Biology http://www.biodigm.com/pope/pope6.htmJohn Innes Centre, Norwich, Norfolk 28 June - 1 July 1997 CALL FOR ABSTRACTSConference Offer: 1995 (Oxford) Perspectives (Hardback) book free to thoseregistering early (while stocks last).Please note that a FULL and printable copy of this is available on the World Wide Web at the URL: http://www.biodigm.com/pope/pope6.htm There is also an ON-LINE registration form and abstract submission form for your convenience. Pictures and maps of the venue are available at the Web site.DESCRIPTION AND AIMSThe 5th Perspectives on Protein Engineering Conference held in Montpellier, France, had a special European significance, despite being open to delegates world-wide. This was one of the few occasions when representatives of nearly all the Structure and Function of Proteins projects funded by the European Commission under Framework 3 came together in a 3-day 'meta-network', holding project meetings and contributing to the conference as a whole. With the huge technology push imparted by the success of world sequencing programmes the importance of structural biology to science and industrial product development is obvious. It might be exemplified especially by the havoc caused in Europe by BSE where disastrous social and economic consequences sprung from an as yet unknown, but inappropriate protein folding. The European Commission will publish the results of a survey on Structural Biology in Europe in January 1997. This will certainly be used to assist the development of a Work Programme for Framework 5. The Norwich conference will therefore focus on the topics identified in this survey as being of key scientific and commercial importance.WHO SHOULD ATTENDThis conference will be of particular interest to structural and computational biologists, protein chemists as well as those interested in genetic engineering of plants and micro-organisms for pharmaceutical, industrial and food applications. As well as basic researchers, there will be a strong participation by delegates from the pharmaceutical and biotechnology industries and it is hoped to stimulate more transnational (especially EU) research contacts and collaborations. PRELIMINARY PROGRAMME - ABSTRACTS INVITEDSat 28 June 2 pm - 7:00 pm registration 7:00 pm onwards Get-together reception__________________________________________________________________ Sun 29 June The Challenge of Information 9:00 am - 12:30 pmPosters & Multi-choice Sessions 14:30 - 10:00 pm Bioinformatics collaboration via the World Wide WebMembrane receptor protein over-expression & purificationAdvances in characterization by mass spectrometryMetal centres in proteinsEU Structural Biology Industry Platform Mon 30 June The Challenge of Design & Expression 9:00 am - 6:00 pm Plenary lectureIain Campbell (Oxford. UK) Design & evolution of protein domainsTue 1 July_____________________________________________________The Challenge of Engineering: Relating Structure to Function 9:00 am - 5:30 pm Wed 2 July Possibility of lab visits and meetings________________________________________________________ABSTRACTS FOR LECTURES AND POSTERSFree communications are an important part of the conference. Early submissions will be considered for oral presentation if particularly relevant or interesting (Deadline for consideration for oral communications: 28 February 1997). Abstracts up to 200 words should be sent be e-mail to the secretariat as soon as possible. If you cannot submit the abstract yet, please provide a working title and the authorís names and host organizations. Please indicate the presenting authorís name. If e-mailing your abstract is difficult, print it at at least 11 point font size on A4 paper and send by post for scanning. The deadline for receipt of abstracts for the printed programme is April 30th 1997. PUBLICATIONThis conference will be published electronically. The last conference offered unique world-wide on-line abstracts and a ground-breaking hybrid Web/CD-ROM! This time, abstract titles will be placed at the conference Web site. Delegates who wish to present a short report (2 A4 pages equivalent) or a full paper (up to 10 A4 pages equivalent) should prepare this using the templates available at the conference world wide web address (or if necessary request by e-mail from the secretariat). The paper must be readable using a world wide web browser (html). Please place your the completed paper on your departmental or host institutionís server and e-mail the appropriate URL to the secretariat. The deadline for completing short reports or full papers is April 30th 1997 The full conference programme with all submitted abstracts and links to the short reports and full papers will be published and the address and access details supplied to delegates only in the first week of May 1997. The organisers reserve the right to refuse publication if on review a short report or paper appears not to be relevant to this conference, to be inaccessible or to be scientifically unsound or of unsatisfactory standard. Papers accepted for publication following review will eventually be incorporated as a citeable, permanent publication on CD-ROM abstracted in Chem. Abs. and made available to the major lending libraries or for purchase direct from the secretariat.POSTERSPoster dimensions should be no more than 117cm (tall) by 87cm (wide) and will be attached by Velcro (TM) supplied by the organizers.WORKSHOPSWhere there are concurrent sessions arranged, please indicate which you would be likely to attend. The organizers would be pleased to hear of anyone who wishes to organise a small meeting of relevance to the conference programme either as a satellite meeting or concurrently with the scientific sessions. Please contact the secretariat as soon as possible with an indication of the numbers which may be involved.SOCIAL EVENTS & VISITSThere will be a get-together reception on Saturday evening from 7:30 pm. A barbecue will be available in the Centre grounds on Monday evening. Delegates have access to a bar and swimming pool from the close of the sessions on that day. Tours and visits to the John Innes Centre, the Institute for Food Research and University of East Anglia are being planned for Wednesday morning. Information about the research, facilities and staff at these major centres can be obtained through the links at the conference World Wide Web site and will be available at the conference.ACCOMMODATION & MEALSIt is expected that most people will elect to stay on Campus. The University of East Anglia offers good-sized, comfortable en-suite single rooms at a very reasonable rate, breakfast is included. The supply of rooms is limited and will be allocated on a first-come first served basis. Tea and coffee-making facilities are available and there are comfortable lounges. Morning and afternoon drinks and buffet luncheons will be served in the conference centre. There are a variety of restaurants and diners on campus to choose from in the evening as well local inns and restaurants. There will be information about off-campus dining at the conference reception area. Arrangements will be made with local hotels for those wishing to stay off site or wanting twin or doubled bedded accommodation. If you know you want hotel accommodation, please indicate your requirements and the price range requested. Delegates are at liberty to make their own accommodation arrangements.TRANSPORTThe Conference Centre is about 6 minutes walk through parkland from Campus accommodation. As it is summer, it is anticipated that most people will wish to walk to and from the Centre at their convenience. Please indicate on the registration form if you know you will need assistance for this journey. There are regular bus services from Campus between the City Centre, the railway station and Norwich Airport. Expected bus journey times between Campus and city are about 25 mins and Campus and airport around 45 minutes. Taxis services are also available.TOURISM & VISITSVisitors from outside UK especially should try to stay another day or so. Norfolk is UKís best kept secret - there are more things to visit in a small area than almost anywhere else in the UK. Given limited, time visitors would want to visit Norwich which is a medieval city with narrow cobbled street and a fine castle and cultural centre. Accompanying persons could spend two days visiting and shopping in the city. On the doorsteps of Norwich lies one of Britainís newest National Parks - the Norfolk Broads - a network of waterways meandering through attractive gardens, woodland and small towns and villages. Boating on the Broads is a famous English activity and boats of all types are available for hire from one hour to one week. For naturalists, the Norfolk coastline is renowned for its bird reserves and small seaside towns or ports. Best of all, the conference is scheduled at a time when the weather should be fine but before the main holiday season. It should not be difficult to book accommodation, tours or river trips at this time of the year and the excellent information centre in Norwich will help you find exactly what you want. To help you make longer-term plans, tourist information, accommodation addresses and other contact information is placed on line at the conference World Wide Web address.TRAVELNorwich is 115 miles from London, 184 miles from Manchester and 160 miles from BirminghamBY AIRNorwich Airport has flights from Aberdeen, Edinburgh, Humberside, Teeside and international connections through direct flights from Amsterdam Schipol airport (flight time=25 minutes).From London Stansted airport: A coach service operates to Norwich from the coach station at the airportFrom London Heathrow airport: By train to Norwich from London Liverpool St.Carrier for European flights: AirUK (enquire about concessions). Times are shown below but accurate flight schedules can be found at any time on the AirUK Home Page Bookings made be made through offices in the UK and continental Europe from reservation numbers shown on the AirUK Home Page. (www.airuk.co.uk)Flights from Amsterdam Schipol International AirportSaturday and Sunday (09:45; 14:40 and 19:30)If you provide early notice of when you want to travel, it may be possible to arrange party bookings at lower cost.BY COACHCoaches to Norwich run from most major UK citiesBY TRAINThere is an hourly train service from London (all days except Sundays). The journey takes approximately 1 hour 50 minutes. An Intercity link connects the Midlands and the North via Peterborough.BY SEAThe east coast ports of Harwich and Felixstowe have regular sailings to and from Holland, Belgium and ScandinaviaREGISTRATION FEESThe full registration fee includes access to the lectures, conference programme book, electronic publication services, get-together reception, refreshments and buffet luncheons from Sunday to Tuesday. Accompanying persons fees do not include access to the lectures, meals or refreshments, but include a local information pack and an invitation to the get-together reception on Saturday evening.***All those registering for this conference are offered a complimentary volume of the 1995 Perspectives on Protein Engineering book (335 pages, Hardback) on a first come, first served basis while stock lasts. This can be collected at the meeting or sent on registration (we just ask you to cover postage in this case). POPE 6 REGISTRATION / RESERVATION FORMPlease print or type:Title (circle) Prof. Dr. Mr. Ms. Mrs. Last name: First name_______________________________Middle initial_____Department__________________________________________________Organisation________________________________________________Mailing address_________________________________________________________________________________________________________City________________________________________________________State/county_________________________Pcode/zip______________Phone_________________________Fax___________________________Email_______________________________________________________If claiming graduate student concession please provide supervisoror mentor's name ____________________________________________and enclose letter of recommendation.If accompanied by an associate, please provide name to appear on badge:______________________________________________________________Conference CommunicationsI would like to submit an abstract for consideration as a Paper | Short Communication | Poster (circle one or more)This accompanies my application or will be forwarded by | post | e-mail (circle one only) see notes on abstract preparation and submission in the text.Accommodation requestPlease reserve me ensuite accommodation for the nights of:June 28 | 29 | 30 | July 1 | 2 (circle dates required)If hotel accommodation required then circle category:2* | 3* | 4* | single | double | twin (subject to availability)Conference prices (in UK pounds Sterling; payment in full by April 30th)Registration (includes buffet lunches)Standard: 260 (50 deposit reserves) ___Graduate: 175 (50 deposit reserves) ___Accompanying person: 40 ___Conference social & barbeque 18 ___AccommodationOn-site en-suite single (32 per night; 50 deposit required) ___ Off-site hotel single (45-75 per night 100 deposit required) ___Publications 1995 Perspectives book (posted) 3 (UK) 5 (EU) 10 (worldwide) ___1996 Perspectives CD-ROM 54 worldwide ___1997 Perspectives CD-ROM (discount)45 worldwide ___TOTAL ___EITHER: I enclose a cheque for___________ payable to:"Perspectives Conference" in UK pounds Sterling(USA dollar equivalent accepted if drawn on USA bank).If making a bank transfer please mail a copy of the transfer document(the bank will provide this).OR: Please charge my:Access | Visa | Mastercard | Eurocard (circle one only)the sum of: ____ (pounds Sterling)Name on Card:___________________________________________Card Number:____________________________________________Expiry Date:____________________________________________Cardholder signature:___________________________________Cardholder account address:____________________________________________________________________________________________________________________________________________ Conference Account Name: "Perspectives Conference". Bank code No. 60-02-41 Account No. 21532737. Bank:National Westminster, 27, Market Place, Bingham, NG13 8AN, UKPlease return this form by post (or fax if making a credit card payment) to:POPE 96 Secretariat, c/o BIODIGM, 64, Langdale Grove, Bingham, NG13 8SS, UKInternational Fax: +44 1 949 876 156 UK Fax: 01949 876 156 E-mail: biodigm@dial.pipex.com____________________________ END _________________________

Registration :
Secretariat: POPE '97 c/o BIODIGM, 64, Langdale Grove,Bingham, NG13 8SS, UK Fax: +44 1949 876 156ON-LINE: http://www.biodigm.com/pope/pope6.htm

Deadline for Abstracts: 30 April 1997

Email for Requests and Registration: biodigm@dial.pipex.com

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