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Molecular Advances in Cancer Epidemiology and Prevention

University of California San Francisco , San Francisco, California, U.S.A.
February 20-22, 1997

Invited Speakers: Paul R. Billings, M.D., Ph.D., Veterans Affairs Medical Center, Palo Alto, CA
Suzanne Dee, Ph.D., Staff Scientist, Affymetrix, Santa Clara, CA
Virginia L. Ernster, Ph.D., Professor of Epidemiology, Department of
Epidemiology and Biostatistics, School of Medicine, University of California
San Francisco
David J. Hunter, Sc.D., M.B., Assistant Professor of Medicine, Channing
Laboratory, Boston, MA
Karl T. Kelsey, M.D., Division of Occupational Medicine, Harvard School of
Public Health, Boston, MA
Stephanie J. London, Ph.D., NIEHS, Research Triangle Park, NC
M. Michele Manos, Ph.D., M.P.H., Kaiser Permanente, Oakland, and
Department of Epidemiology and Biostatistics, School of Medicine, University
of California San Francisco
Frank McCormick, Ph.D., Director Designate, Cancer Research Institute,
School of Medicine, University of California San Francisco
Robert C. Millikan, D.V.M., M.P.H., Ph.D., Department of Epidemiology,
University of North Carolina, Chapel Hill, NC
Nicholas L. Petrakis, M.D., Emeritus Professor, Department of
Epidemiology and Biostatistics, University of California San Francisco.
Nathan Rothman, M.D., M.P.H., M.S.H., NIH/National Cancer Institute
David Sidransky, M.D., Department of Otolaryncology, Johns Hopkins
University, Baltimore, MD
Jean Simpson, M.D., City of Hope, Duarte, CA
Jack A. Taylor, M.D., Ph.D., NIEHS, Research Triangle Park, NC
Neil W. Toribara, M.D., Ph.D., Assistant Adjunct Professor,
Gastroenterology, Department of Medicine, University of California San
Francisco and VAMC
Alice S. Whittemore, Ph.D., Professor, Department of Health Research and
Policy, Stanford University School of Medicine
Margaret R. Wrensch, Ph.D., Associate Professor, Department of
Epidemiology and Biostatistics, University of California San Francisco

Program:
Thursday, February 20, 1997

DISEASE PATHWAYS AND GENE PRODUCTS, I

1:00 Welcome and Introduction
John K. Wiencke, Ph.D.

1:05 Overview
Frank McCormick, Ph.D.

1:45 Keynote Address
From Basic Research to Cancer Prevention
David Sidransky, M.D.

2:45 Questions and Discussion

2:55 Break

Epidemiology of Prostate Cancer and PSA Testing
Alice S. Whittemore, Ph.D.

4:00 Questions and Discussion

4:10 Molecular Epidemiology of Papilloma Virus and Cervical Cancer
M. Michele Manos, Ph.D., M.P.H.

4:50 Questions and Discussion

5:00 Adjourn

Friday, February 21, 1997

DISEASE PATHWAYS AND GENE PRODUCTS, II

Mutational Spectra: Insights into Causation and Prognosis
Moderator: Karl T. Kelsey, M.D.

8:00 p53 Gene Alterations and Cancer Etiology
Jack A. Taylor, M.D., Ph.D.

8:40 Questions and Discussion

8:50 p53 Gene Alterations: Correlations with Survival and
Therapeutic Response
Karl T. Kelsey, M.D.

9:30 Questions and Discussion

9:40 Break

Breast Cancer Screening: Controversy and the Promise of Molecular
Markers
Moderator: Nicholas L. Petrakis, M.D.

10:00 Epidemiology of Ductal In Situ Carcinoma of the Breast
Virginia L. Ernster, Ph.D.

10:40 Questions and Discussion

10:50 Molecular Markers of High-risk Lesions in Breast Cancer
Jean Simpson, M.D.

11:30 Questions and Discussion

11:40 Lunch Break

GENETIC SUSCEPTIBILITY, I

Highly Penetrant Cancer Susceptibility Genes
Moderator: John K. Wiencke, Ph.D.

1:00 Genetic Markers and Screening in Familial Colon Cancer
Neil W. Toribara, M.D., Ph.D.

1:40 Questions and Discussion

1:50 Heritable Mutations in BRCA1 and BRCA2 in Breast Cancer
David J. Hunter, Sc.D., M.B.

2:30 Questions and Discussion

2:40 Break

3:00 Emerging Technologies for Genetic Analysis: Applications of the
GeneChip System to the p53 Gene
Suzanne Dee, Ph.D.

3:40 Questions and Discussion

3:50 Genetic Testing for Cancer Risk: Clinical and Ethical Considerations
Paul Billings, M.D., Ph.D.

4:30 Questions and Discussion

4:40 Adjourn

Saturday, February 22, 1997

GENETIC SUSCEPTIBILITY, II

Genetic Modifiers and Gene-Environment Interaction
Moderator: Margaret R. Wrensch, Ph.D.

8:00 Methodologic Issues in Biomarker Studies of Gene-
Environment Interactions
Robert C. Millikan, D.V.M., M.P.H., Ph.D.

8:40 Questions and Discussion

8:50 Tobacco-related Cancers and Polymorphisms in Genes Encoding
Carcinogen-metabolizing Enzymes
Stephanie J. London, Ph.D.

9:30 Questions and Discussion

9:40 Break

10:00 Molecular Markers in Occupational Epidemiology and Leukemia
Nathan Rothman, M.D., M.P.H., M.S.H.

10:40 Questions and Discussion

11:00 Adjourn

PROGRAM CHAIRS
Thursday, February 20, 1997

DISEASE PATHWAYS AND GENE PRODUCTS, I

1:00 Welcome and Introduction
John K. Wiencke, Ph.D.

1:05 Overview
Frank McCormick, Ph.D.

1:45 Keynote Address
From Basic Research to Cancer Prevention
David Sidransky, M.D.

2:45 Questions and Discussion

2:55 Break

Epidemiology of Prostate Cancer and PSA Testing
Alice S. Whittemore, Ph.D.

4:00 Questions and Discussion

4:10 Molecular Epidemiology of Papilloma Virus and Cervical Cancer
M. Michele Manos, Ph.D., M.P.H.

4:50 Questions and Discussion

5:00 Adjourn

Friday, February 21, 1997

DISEASE PATHWAYS AND GENE PRODUCTS, II

Mutational Spectra: Insights into Causation and Prognosis
Moderator: Karl T. Kelsey, M.D.

8:00 p53 Gene Alterations and Cancer Etiology
Jack A. Taylor, M.D., Ph.D.

8:40 Questions and Discussion

8:50 p53 Gene Alterations: Correlations with Survival and
Therapeutic Response
Karl T. Kelsey, M.D.

9:30 Questions and Discussion

9:40 Break

Breast Cancer Screening: Controversy and the Promise of Molecular
Markers
Moderator: Nicholas L. Petrakis, M.D.

10:00 Epidemiology of Ductal In Situ Carcinoma of the Breast
Virginia L. Ernster, Ph.D.

10:40 Questions and Discussion

10:50 Molecular Markers of High-risk Lesions in Breast Cancer
Jean Simpson, M.D.

11:30 Questions and Discussion

11:40 Lunch Break

GENETIC SUSCEPTIBILITY, I

Highly Penetrant Cancer Susceptibility Genes
Moderator: John K. Wiencke, Ph.D.

1:00 Genetic Markers and Screening in Familial Colon Cancer
Neil W. Toribara, M.D., Ph.D.

1:40 Questions and Discussion

1:50 Heritable Mutations in BRCA1 and BRCA2 in Breast Cancer
David J. Hunter, Sc.D., M.B.

2:30 Questions and Discussion

2:40 Break

3:00 Emerging Technologies for Genetic Analysis: Applications of the
GeneChip System to the p53 Gene
Suzanne Dee, Ph.D.

3:40 Questions and Discussion

3:50 Genetic Testing for Cancer Risk: Clinical and Ethical Considerations
Paul Billings, M.D., Ph.D.

4:30 Questions and Discussion

4:40 Adjourn

Saturday, February 22, 1997

GENETIC SUSCEPTIBILITY, II

Genetic Modifiers and Gene-Environment Interaction
Moderator: Margaret R. Wrensch, Ph.D.

8:00 Methodologic Issues in Biomarker Studies of Gene-
Environment Interactions
Robert C. Millikan, D.V.M., M.P.H., Ph.D.

8:40 Questions and Discussion

8:50 Tobacco-related Cancers and Polymorphisms in Genes Encoding
Carcinogen-metabolizing Enzymes
Stephanie J. London, Ph.D.

9:30 Questions and Discussion

9:40 Break

10:00 Molecular Markers in Occupational Epidemiology and Leukemia
Nathan Rothman, M.D., M.P.H., M.S.H.

10:40 Questions and Discussion

11:00 Adjourn

Registration :
COURSE REGISTRATION

Molecular Advances in Cancer Epidemiology and Prevention
February 20-22, 1997

Mail to: Office of Continuing Medical Education
Registration Office
UCSF Box 0742, MCB 630
San Francisco, CA 94143-0742
Fax: 415/476-0318

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HOTEL RESERVATIONS
Molecular Advances in Cancer Epidemiology and Prevention
February 20-22, 1997

Mail to: The Sheraton Palace
Reservations Department
2 New Montgomery (at Market)
San Francisco, CA 94105
Tel: (800) 325-3535
Fax: (415) 543-0671

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Room Rates (Subject to City Hotel Tax):
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Please check desired accommodations. Reservations must be received by
January 21, 1997. You must identify yourself as a member of this conference to
receive the special rate. Reservations are held only until 4:00 p.m. unless one
night's deposit is received or payment guaranteed with a credit card.

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Deadline for Abstracts: none

Email for Requests and Registration: jwiencke@epi.ucsf.edu


Posted by: John K. Wiencke, Ph.D. Host: junior-21.ucsf.EDU date: January 14, 97 0:59:56
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