Program:
Proteins represent one of the most essential biological building blocks, and thus proteases, which are capable of restructuring proteins, are one of the most powerful tools in health or disease. The identification of a number of disease conditions under which proteases are critical for disease pathology continues to grow and now includes such fundamental indications as metastasis, inflammation, cytokine processing, HIV and other infections, as well as others. Designing or screening for selective antagonists of key proteases has become an attractive course for new drug development. This program is designed to integrate what can be learned from the efforts under way with a variety of protease targets that should improve the efficiency with which better inhibitors and new protease targets might be pursued. Coverage will include inhibition of matrix metalloproteases, cytokine convertases, coagulation cascade proteases, calpain, clipsin, and viral proteases, as well as more basic studies that can be applied to a range of such targets.
Registration :
Cambridge Healthtech Institute
1037 Chestnut Street
Newton Upper Falls, MA 02164 USA
tel: 617-630-1300
fax: 617-630-1325
Deadline for Abstracts: 9/96
Email for Requests and Registration: chi@healthtech.com