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Gordon Research Conference on Intermediate Filaments

Gordon Reseach Conference , Holderness, N.H. USA
14 July - 19 July, 1996

Invited Speakers: Ueli Aebi (U. Basel)(chair) - Structural studies on IFs *
Klaus Weber (Max Planck Institute) - IF proteins in invertebrates
Harald Herrmann (German Cancer Res. Center) - Assembly mechanism of wild-type & domain-mutated intermediate filament proteins
Nobataka Hirokawa (U. Tokyo) - Structural studies on neuronal IF proteins
Howard Worman (Columbia U). - Human nuclear lamins & the lamina-associated Protein LBR
Christopher Hutchison (U. Dundee) - The organisation of 13nm filaments within the nucleus and their influence on DNA replication.
Robert Evans (U. Colorado Health Sci. Center)(chair) - Vimentin and lipid metabolism
Zendra Zehner - Regulation of vimentin expression)
Masaki Inagaki (Tokyo Met. Inst. Gerontology) - Post-translational modification & IF network reorganization
Gregg Gundersen (Columbia U.) - Regulation of IF distribution by tubulin post-translational modification
Alice Fulton (U. Iowa) - The site of IF synthesis affects cell phenotype
Charles Babinet (Inst. Pasteur)- Further studies on the vimentin knock-out mouse.
Ron McKay (NIH) - Regulation and function of nestin
Ron Liem (Columbia U.)(chair) - Assembly and phosphorylation of neuronal IF.
Michael Brenner (NIH) - GFAP gene expression and function
Shigeyoshi Itohara (Kyoto Univ.) - Characterization of the GFAP knock-out mouse
Milos Pekny (U. Gothenburg) - GFAP deficient mice as a tool to address functions of astrocytes in vivo.
Harish Pant (NIH) - Modification of neurofilament proteins by CDKs
Ralph Nixon (McLean Hospital, Harvard Med. School) - Neurofilament dynamics and modification.
Don Cleveland (UCSD)(chair) - NF-dependent structuring of the axon: order and disorder in the axoplasm
Jean-Pierre Julien (McGill University) - Knock-out mutagenesis of NF genes in mice
Greg Elder (Mt. Sinai, N.Y.) - Knockout mutagenesis of NFH in mice.
Thomas Shea - Dynamics of neuronal intermediate filament proteins
Virginia Lee (U. Pennsylvania) - NFs and animal modess of human neurodegenerative diseases
George Perry (Case Western Res. Univ.) - Oxidative modification of neurofilaments in Alzheimer and other neurodegenerative diseases.
Don Cleveland (UCSD)(chair) - NF-dependent structuring of the axon: order and disorder in the axoplasm
Jean-Pierre Julien (McGill University) - Knock-out mutagenesis of NF genes in mice
Greg Elder (Mt. Sinai, N.Y.) - Knockout mutagenesis of NFH in mice.
Thomas Shea - Dynamics of neuronal intermediate filament proteins
Virginia Lee (U. Pennsylvania) - NFs and animal modess of human neurodegenerative diseases
George Perry (Case Western Res. Univ.) - Oxidative modification of neurofilaments in Alzheimer and other neurodegenerative diseases.
Elaine Fuchs (HHMI/U. Chicago)(chair) - Functions of cytoskeletal-membrane connector proteins.
Dennis Roop (Baylor University) - Epidermal keratins, regulation and function.
Irvin McLean (U. Dundee) - Mutations in specific keratins lead to a range of human epithelial fragilities.
Dietmar Mischke (Humboldt University, Germany) - Keratin genes & the epidermal differentiation complex: gene families involved in epithelial differentiation.
John Compton (NIH) - Genetic diseases of epithelial differentiation: keratins & other culprits.
Michael Klymkowsky (U. Colorado, Boulder)(chair) - The IF-membrane nexus as a structural and a signaling center.
Yasemi Capetanaki (Baylor) - Desmin in the control of myogenesis
Denise Paulin (Inst. Pasteur) - Knock-out mutagenesis of desmin and human myopathic conditions.
David Garrod (U. Manchester) - Regulation of desmosomal adhesion in development & differentiation.
Roger Buxton/Terry Magee (NIMR, UK) - Desmosomal cadherins in the embryo and the heart.
Omar Skalli (U. Illinois at Chicago) - The role of IFAP 300 in anchoring IF to adherens junctions.
Pam Cowin (NYU)(chair) - Desmosomal cadherin-catenin-IF interactions
Margeret Wheelock (U. Toledo) - Interactions between cadherins and their associated proteins.
W.James Nelson (Stanford Univ.) - The pathway of adherens junction assembly.
Kathleen Green (Northwestern Univ.)- Assembly of intercellular adhesive junctions: sorting out who's who
Sergie Troyanovsky (Washington Univ., St. Louis) - Mapping the interactions between desmosomal cadherins and their catenins.
Poster Discussion: Mechtchild Hatzfeld (Max Planck Inst., Germany)
Sypros Georgatos (EMBL, Germany)
Conference summary: Robert D. Goldman (Northwestern University)
Werner Franke (German Cancer Rese. Center, Heidelberg.)


Program:
Evolution and structure of IF proteins & nuclear lamins.
Vimentin & Nestin: expression, organization & functions.
GFAP & neuronal IF & modifications
Neuropathology & IFs
Transgenic studies of keratin function
Keratins & their associated proteins in human disease.
Desmin & Desmosomes
PosterPresentiation/ Discussion
IF-membrane interactions



Registration :
Contact: Mike Klymkowsky
(klym@spot.colorado.edu)
or the GRC registration center
@GRCMAIL.GRC.URI.EDU

Deadline for Abstracts: the end of June, 1996

Email for Requests and Registration: klym@spot.colorado.edu


Posted by: Mike Klymkowsky Host: tele-anx0226.Colorado.EDU date: April 05, 96 14:30:33
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