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Interface of Biomechanics and Cell Biology in Orthopaedics

JOHNS HOPKINS MEDICAL INSTITUTIONS , BALTIMORE, MD
JUNE 6-8, 1996

Invited Speakers: JOHNS HOPKINS FACULTY


Edmund Y.S. Chao, Ph.D.
Professor of Orthopaedic Research and Mechanical Engineering

Donald S. Coffey, Ph.D.
Professor of Pharmacology, of Urology and of Oncology

A. Hari Reddi, Ph.D.
Professor of Orthopaedic Research and Biological Chemistry

Richard N. Stauffer, M.D.
Professor and Chairman of Orthopaedic Surgery


GUEST FACULTY:

Harold M. Aberman, D.V.M.
Director, Howmedica Inc.
Rutherford, New Jersey

Albert Banes, Ph.D.
Professor of Orthopaedic Surgery
University of North Carolina
Chapel Hill, North Carolina

Henry J. Donahoe, Ph.D.
Associate Professor of Orthopaedics and of Cellular and Molecular Physiology
Hershey Medical College
Pennsylvania State University College of Medicine
Hershey, Pennsylvania

John H. Dumbleton, Ph.D.
Senior Vice President, Howmedica Inc.
Rutherford, New Jersey

Randy Duncan, Ph.D.
Assistant Professor of Orthopaedic Surgery and of Physiology and Biophysics
Indiana University School of Medicine
Indianapolis, Indiana

Steven A. Goldstein, Ph.D.
Professor of Surgery
Director of Orthopaedic Research
University of Michigan Medical School
Ann Arbor, Michigan

Alan J. Grodzinsky, Ph.D.
Professor of Electrical, Mechanical and Bioengineering
Massachusetts Institute of Technology
Cambridge, Massachusetts

Farshid Guilak, Ph.D.
Associate Professor of Orthopaedic Surgery
Duke University
Durham, North Carolina

John E. Herzenberg, M.D.
Associate Professor of Orthopaedic Surgery
University of Maryland
Baltimore, Maryland

Donald Ingber, M.D.
Associate Professor of Pathology
Harvard Medical School
Boston, Massachusetts

Lance Lanyon, Ph.D.
Professor, Royal Veterinary College
University of London
London, England

Van C. Mow, Ph.D.
Professor of Orthopaedic Surgery
Columbia University
New York, New York

Glenn F. Pierce, M.D., Ph.D.
Vice President
Prizm Pharmaceuticals
San Diego, California

Clinton T. Rubin, Ph.D.
Professor of Orthopaedics
State University of New York
Stony Brook, New York

Robert L.-Y. Sah, M.D., Ph.D.
Assistant Professor of Bioengineering
La Jolla, California

Jonathan L. Schaefer, M.D.
Assistant Professor of Orthopaedic Surgery
Brigham and Women's Hospital
Boston, Massachusetts

Tim Skerry, Ph.D.
Professor of Biology
York University
York, England

Ross A. Tubo, Ph.D.
Director, Genzyme Tissue Repair, Inc.
Framingham, Massachusetts

Charles H. Turner, Ph.D.
Professor of Orthopaedics
Indiana University School of Medicine
Indianapolis, Indiana

Kathryn G. Vogel, Ph.D.
Professor of Biology
University of New Mexico
Albuquerque, New Mexico

Savio L.-Y. Woo, Ph.D.
Professor of Orthpaedic Surgery
Pittsburgh University
Pittsburgh, Pennsylvania

Natsuo Yasui, M.D.
Professor, Osaka Medical Center
Osaka, Japan

Program:
The optimal clinical outcome of orthpaedic implants in orthopaedic surgery is critically dependent on synergism of biomechanics and responding cellular response. This conference will focus on the interface of biomechanics, cell biology and growth factors. The emphasis will be on how mechanical signals influence cells and attendant gene expression. Therefore, attention will be focused on how mechanical signals interact with cell surface receptors, extracellular matrix, cytoskeleton and nuclear matrix. The sessions deal with:



Cell Biological Principles

Growth and Morphogenetic Proteins

Cartilage

Mechanical Loading

OBJECTIVES

The conference will seek to:



* Identify novel approaches to the design of orthopaedic implants based on biomechanics and cell biology

* Recognize the research priorities in the interface of biomechanics, cellular response and growth factors

* Stimulate new research directions and collaboration between industry and academia in the actions of mechanical stimuli on musculoskeletal tissues, and

* Provide research recommendations for new interdisciplinary approaches.

Registration :
Fees:


Clinicians and Academicians $400
Industry $700
Residents, Fellows, and Students $200
(with letter from department chairperson verifying status.)

Please note that on-site registrations will be assessed a $15 charge.

The registration fee, which is payable in advance, includes instructional materials, refreshment breaks, luncheons and
the banquet. Foreign payments must be made on a U.S. bank.

Cancellation Policy: An administrative fee of $50 will be retained on all refunds. Refunds are not possible unless
notice of cancellation is received one business day prior to June 1, 1996. Refunds will be processed upon receipt
of a cancellation letter. The Johns Hopkins University reserves the right to cancel this course at any time.
In this event, the full registration fee will be returned to the registrant.




CONTINUING MEDICAL EDUCATION CREDIT


The Johns Hopkins University School of Medicine is accredited by the
Accreditation Council for Continuing Medical Education to sponsor medical education
for physicians.



The Johns Hopkins University designates this continuing medical education activity for
22 credit hours in Category I of the Physician's Recognition Award of the American
Medical Association.



This program has been approved for 2.2 Continuing Education units.

Deadline for Abstracts: tba

Email for Requests and Registration: dheaphy@SOM.adm.jhu.edu


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