Invited Speakers: Cheryl H. Arrowsmith (Ontario Cancer Institute, Toronto, Canada)
Ivano Bertini (Universita degli Studi di Firenze, Italy)
Richard R. Ernst (ETH Zentrum, Zurich, Switzerland)
Hans Frauenfelder (Los Alamos National Laboratories, USA)
Cornelius W. Hilbers (University of Nijmegen, The Netherlands)
Oleg Jardetzky (Stanford University, USA)
Jean-Francois Lefevre (Universite Louis Pasteur, France)
Michael Levitt (Stanford University, USA)
William N. Lipscomb (Harvard University, USA)
Dino Moras (Universite Louis Pasteur, France)
Joseph D. Puglisi (Stanford University, USA)
Paul Rosch (Universitat Bayreuth, Germany)
Brian D. Sykes (University of Alberta, Edmonton, Canada)
Wilfred van Gunsteren (ETH Zentrum, Zurich, Switzerland)
Program:
EXPERIMENTAL OBSERVATION OF MOLECULAR MOTIONS
•Modern NMR techniques: 3D spectroscopy and molecular dynamics
•Protein crystallography
•Multisubunit allosteric proteins
OBSERVATION OF INTERNAL MOTIONS OF BIOLOGICAL MOLECULES
•Dynamics and conformational transitions in allosteric proteins
•Principles of NMR and dynamics
•Protein dynamics and reactions
•The energy landscape of proteins
THEORETICAL ANALYSIS OF INTERNAL MOTIONS IN BIOLOGICAL MOLECULES
•Introduction to molecular dynamics
•Simulations of protein folding
•Simulating protein and nucleic acid molecular dynamics
•New programs in MD simulations
•Calculation of free energy and binding constants
MOTIONS IN NUCLEIC ACID
•Nucleic acids structure and dynamics
•RNA NMR spectroscopy
ANALYSIS OF SPECIFIC PROTEINS
•Interactions of antifreeze proteins with ice
•Mechanism of action of calcium-signaling proteins
•tat-Protein structure, dynamics and function
•Protein-DNA complexes: Heteronuclear strategies of the assignment of larger complexes
Registration :
Course fee of $1,200 US includes full board and lodging at Ettore Majorana Centre and
transportation from Palermo airport to Erice.
On-line at URL listed above or by email to reh@stanford.edu
send:
1) date and place of birth and nationality
2) degree and other academic qualifications
3) list of publications
4) present position and work address, fax and phone numbers and email address
Young applicants with only a few years of experience in the field should arrange for a letter of recommendation from the head of their research group.
Applicants interested in financial aid should also send an abstract of current research interest. Selected papers will be presented in poster sessions and student workshops.
Deadline for Abstracts: March 15, 1999
Email for Requests and Registration: reh@stanfod.edu