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1440 Barberry Dr.
We are in the process of consulting future licensing manufacturers for subsidiaries.
We are gathering business intelligence near Boston, MA USA that our LED laser can be developed in the USA (with Raccoon InfoSyse as the Canadian & Philippine manufacturing subsidiaries).
We will contact candidates to be licensed exclusively with use of our dye-tagged denaturing polyacrylamide electrophoretic (DT-DPAGE) protocol which beats the competition for fast turn around of our gel runs and ease of use otherwise not available and will facilitate faster multiple runs for high-throughput proteomic analysis.
Additionally it is requisite that the electrophoretic mechanism be "pulsed" to define greater resolution and finer discrete gel bands for direct visual ID and reading capacity through the laser reader.
Design of our digital densitometric scanner also called the PS2 Rubicon Digitizer provides two (2) formats:
(1) DM = desktop mounted for lab bench
(2) M = mobile dedicated device for biofermentation design, scale-up and prototyping and routine monitoring for production
And can define DNA Sequencing in variable size formatting. It is likely the first invited use will be for pharma application at our subsidiary covered by Genus Farms Milling and Foods Canada (see: this website).
I LASER's Defn. = light amplified by stimulated emission of radiation
-Laser is a photonic pulsed laser with focused, sensitive, specific and multiple readings and is accurate.
II LASER Specs.:
The laser specified for this dye-tagged PAGE application (an ene-azo dye tag) is made up of a Argon (Ar) gas laser device with major emitt ing bandwidths of 488nm and 514nm possibly where the pink to red dye-tag absorbs. We have yet to determine the absorption spectrum of the ene-azo dye-tag making the laser preliminary in choice but keeping in mind the absorption part of the spectrum is broad and powerful at 400 and 550 nm visual.
III MODEL of a Digital Laser Densitometer (Multiplex): GE Amersham Molecular Dynamics Typhoon 9410 Molecular Imager
(Google this entry title for link.)
IV LASER DEVICE's Configuration:
Device is comprised of: a) a solid-state laser(s), Argon (g), b) arcylate sandwich assembly, c) pre-sampling 'kit' (analytes) and d) slotted detector. The translucent gel bands are coloured 'pink' with the laser in major track vs guide mode to make a fixe or balance point by difference.
Cassette (acrylate) is premade together with sample 'kits' using PAGE gel inserts loaded from ontop and run vertically (gravitationally) like a PlayStation 2 (PS2) (R) configured game boy. The laser is shot from behind with detector/chromator slotted in front position together with its WiFi capability.
Apart from being largely solid-state the reader's laser is servo motor driven via electronic control.
LASER & BEAM - to be discussed elsewhere.
DETECTOR - IC - integrated processor.
DATA PROCESSING - Data print out from electronic controlled device.
MODES OF OPERATION - Prep and analytical for food products, biopharma, new transcription factor engineering (TFE) technology, e. g. PNA technology and for biomarkered analytics applications for diagnostics in therapeutics (preventative, interventive, rehabilative).
MAIN COMPUTER - to be HQ'd in a country like Japan with data servers available.
SOFTWARE - Contracted out to London-based subsidiary run in the Philippines.
SKYEVIEW: There is news reaching SkyeBlue of experiments involving livestock cattle and water buffaloes ("carabaos") on SCT/grass silage fed year round for dairy and meat production for the assessment of plasma bovine growth releasing hormone (bGRH) and bovine growth hormone (bGH) with feeding of functional acting non-essential (NEAA) / HIS amino acids and the Principal Investigator's own research interest to assay if HIS in bovine mammalian spp. has a particular effect on hormonal levels and on milk output (Kg/day) and lean body mass/ fat (LBM/fat) composition, including in particular skeletal muscular fibrillar tissues, as indicators of muscular mass' lean gain (LG) and correlations with animal's N status and if any total body weight or gain.
SKYEVIEW: We are just launching these new project ideas for use with Raccoon Info-Systems (see ref. web address here) for new Peptide-Nucleic Acid TFE research technology and applying PCR for proteome plasma analyses for biomarkers in diagnostics for preventative, interventive and rehabilative care.
SKYEVIEW: As a progress report "on the wire" Mexican and Philippine (with British contracting of software for development) interests as probable investors, together with the Japanese/Canadian/American concern, as subsidiaries there for hardware/software manufacturing. Cost/profit projections in the marketplace are to be made before investment commitment. We are unsure of the Principal authors exclusive intentions at this time of manufacturing the reagent kits and other attendant fine chemicals to be supplied by a parent co. We have plans to license out to a holding co. in Canada and the U.S.A. with private party interests on a contractual basis for our purposes. Feasibility studies (this is an extensive one as to protocol and their actual worked out applications of the methods used), and financial planning as to its soundness including indemnity for an insurance policy will have to be studied further. To continue we would manufacture kits that interface with the rest of the parts in the instrumentation hardware and that are adapted to particular applications marketable in the Life Science or Bio/Industries, especially in North America. The more automation (digitization) and the more efficient or faster, the more attractive they will be with the competition. We believe that this is the cheaper alternative in proteomics research.
SKYEVIEW: We have finally connected (a first at "SkyeBlue") with a practitioner entrepreneur based in SG (ASEAN) of the KMP Group (SG) in turn of the SALIM GROUP (Indonesie) regards our affair with a mini protein reader using our exclusive proprietary dye-tagging detergent ("DT") with PAGE electrophoresis and have heard the news that their original MINIPCR for DNA kit will be manufactured from SG with Ampylus of Boston MA USA until end of 2021 and at that time will consider taking up our exclusive offer of perhaps designing a unit reader and manufacturing it together with the completing kit items, viz. the major reagent component being "DT" to be discussed with a larger manufacturer with our exclusive licensing arrangement like BIO-RAD of CA USA. The SALIM Group is now successfully using their own MINIPCR DNA reader for various diagnostics like SARSCov2 and ASFV in ASEAN. Hopefully this whole affair will bear fruit with "SkyeBlue".
SKYEVIEW: Another note on the MINIPROTEIN READER for "DT" and kit is that rather than turning directly to our industry "advisor", Dr. Angelito Ortega Abaoag, of Microbiome Life Sciences Pte. Ltd. (SG), we have decided to approach a chemistry physics engineer professor at the Kyushu University, Fukuoka, Japan on enlisting his expertise and supervision under his own grants for designing the READER as a supposed diode laser for absorption spectrometry with "DT" reagent useful for such applications as processing and food science including vaccines, enzymes, hormones (e. g. insulin), other biopharma and foods including nutraceuticals. The prospectus is large. Dr. Lito Abaoag has hopefully realized that probably an entity like Japan will take over if it doesn't take hold in the Philippines in terms R&D/technology transfer otherwise it will cede to Australia, for eventual use world-wide including ASEAN. We are proposing subsidiaries with larger companies with their umbrella (manpower or expertise and facilities capability) in Japan, Canada, U.S.A., Mexico and home country the Philippines Islands.
(c) D. A. Flores. SKYE BLUE INTERNET. Port Coquitlam. BC. Canada V3B 1G3.
Last update of this entry: August 01, 2021