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An SBO Company
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A proposal for strategic cooperation and investment with Universities & Colleges in the Negros Island region (NIR) of the Philippine Islands with outside investors involved with various technologies for their transfer for advancement, and to increase relevance and to extend their reach in science & technology, making them socio-economically & culturally viable or achievable.
We encourage financially sound investment in partnership with Universities & Colleges as leading Universities in the Philippines have recently declared and established our Project Portfolios for further Development:
1) Arctic-Alpen ICE (Immersion Cold Energy) MicroGen-Technology.
2) Micro-Syntheses of Drug VitD-Agonistes from Plant-based Lanosterol.
3) HQ Debuffered Silages using Micro-Zymogen Technology.
4) Micro-Consortia Using C-Sink Methano-Generation.
5) Micro-Tech with UreaZymogen Technology.
6) Micro-Protect HIS Yeast Technology with Silage in Organic Beef & Dairy.
In all these projects metabolomics, proteomics and genomics with computational bioinformatics will require skills of: mathematicians, physicians, biochemists, microbiologists, agronomists and computer engineers to solve multi-disciplinary problems with probability of finding commercial success. They will support government policy in the Philippines known as STEAM (Science, Technology, Engineering, Agriculture and Mathematics).
The cell cycle and its division or termed 'mitogenic potential' of the cell is regulated, in part, by 'ATP pools' and their feeding into the cell cycle from energy substrate (both protein, carbohydrate and fat) and by measures of the inter-ratio determine availability of either preformed amino acids (i. e. peptides/AA) or water soluble carbohydrates (e. g. FOS or fructan) and their balance of substrate with respect to ATP. In the case excess ATP is produced the ATP 'leaks' from the cells' entity. We will not quote specific studies here but supporting literature is available from 'Skye Blue' upon inquiry. Further investigation is required to document or prove operon control as regulated by substrate availability and to manipulate possibly further boosting the potential of microbial synthesis for microbial cell protein (MCP). The operons may present regulatory 'synergy' between substrates' actions or may act to the 'core' of the cell given amino acids are fundmental to cell structure and mechanism. The extent to which both substrates are in tune with the 'core' cell cycling mechanism remains to be seen.
It was predicted that on two occasions at the masteral level that this 'nuclear' area of research in D. A. Flores' earlier investigation of amino acids and their utilization in regards to feed intake response (as readers may remember all nitrogen (N) balance or status data was 'redacted' due to wrongful reporting, the only revision of the two (2) papers both in reporting these fiindings) and duodenal amino acid flows as an indication of N status in sheep, that employment of PNA-B12 carriers to silence genes in this case to test putative families of transcription factors (TFs) (e. g. three families may be involved each in 'core' metabolic amino acid supply, cell cycling /mitogenesis or water-soluble carbohydrates (e. g. FOS or fructan), or all three, applicable to these metabolic activities are available for investigation for candidate factors with our studies.
The new field or frontier for D. A. Flores' earlier investigation into amino acids and their utilization will encompass: biochemical cell signaling, neurotransmitter function, operon regulation, neurohormonal regulation, immunomodualtion, behavioral aspects in animal production including intake, metabolism in physiology, digestion and LBM/fat accretion or loss as a health & production parameter.
Last update of this entry: July 05, 2020