April, 9 1999
I am trying to help a young man who was investigated for infertility and found to have sertoli-cell-only syndrome. He has had a semen analysis which shows no spermatozoa. Bilateral testicular biopsy shows no germ cells present. He has an older brother who is well, and who is not yet married and has no children. He also has two sisters who each have healthy children.
My patient is very anxious to know the etiology of his infertility. He also wants a cure. He wonders if we cannot simply fix his DNA.
I am in the process of arranging a karyotype and FISH analysis of the
Y chromosome. I am also banking DNA. Is there anyone who is
interested in studying this man's sample? Is there anything I can
offer him? Has anyone had experience of any level of fertility given
Thank you for your help.