HUM-MOLGEN DIAGnostics/Clinical Research

7 May 1997
Ring Chromosome 11

Dear Sir:

We know that at least three cases of ring 11 chromosome with phenotypes compatible with partial monosomy 11q have been reported. We have recently studied a 5-year-old girl referred for evaluation of growth retardation and dysmorphic features. On clinical examination, besides short stature she displayed other typical features of chromosome 11q- syndrome. Cytogenetic analysis confirmed a ring 11 chromosome. I want to know who may perform chromosome 11 specific painting probe and/or molecular studies in this patient and would be interested in a collaborative study.

Prof. Dr. Gerson Carakushansky
Chief of Genetic Services
Instituto de Pediatria da UFRJ
Rio de Janeiro - Brazil
FAX: (5521) 522-3599