HUM-MOLGEN DIAGnostics/Clinical Research

5 December 1996
Patient with 47,XXX,t(8;10)(q22.1;q24.1)

We have seen a 6-year old child with a de novo, apparently balanced, 47,XXX,t(8;10)(q22.1;q24.1) karyotype. Developmental delay, particularly speech, is more severe than one would expect for triple X.
The parents are keen for further work to be done on the translocation. Is anyone interested in a cell line ?

RM Winter,
Mothercare Unit of Clinical Genetics,
and Fetal Medicine,
Institute of Child Health,
30 Guilford Street
London, WC1N IEH
Tel: 0171 242 9789 ext: 2108
Fax: 0171 831 0488