29 November 1996

I am working on the positional cloning of a gene for the Senior-Loken-Syndrome, which is characterized by familial juvenile nephronophtisis (also called medullary cystic disease) and retinitis pigmentosa. We still need some more families for a successful linkage analysis, best with two or more affected members, but single patient families would also be greatly appreciated and any material or information on families is welcome.