HUM-MOLGEN DIAGnostics/Clinical Research

2 March 1998
NEED ADVICE REGARDING BETAINE THERAPY 

Dear Colleague

A 20-year-old patient of ours with 5,10-methylenetetrahydrofolate reductase deficiency is having a very difficult time trying to eat the 6 grams of betaine each day needing to keep her plasma L-homocysteine concentration low.

She has tried mixing it with a variety of solids and liquids, but now gags immediately when she tries to swallow it.

We would be grateful for any suggestions.

Richard W. Erbe,
M.D., Chief, Division of Genetics,
Children's Hospital of Buffalo,
and
Professor of Pediatrics and Medicine,
School of Medicine and Biomedical Sciences,
State University of New York at Buffalo
e-mail: Folate@AOL.COM