HUM-MOLGEN DIAGnostics/Clinical Research

21 April 1997
Leber Hereditary Optic Neuropathy

Dear Colleagues:

I have received a request for molecular diagnostic testing for Leber Hereditary Optic Neuropathy. It is my understanding that this disorder is caused by mutations in the mitochondrial genome, and that there are a few major mutations which one intially analyzes for.
I would greatly appreciate if anyone testing for this disorder who would be willing to accept a patient referral would contact me.

Karl V. Voelkerding M.D.
Medical Director of Molecular Diagnostics
Department of Pathology and Laboratory Medicine
University of Wisconsin Hospital and Clinics
600 Highland Avenue
Madison, Wisconsin 53792-2472
Office (608) 263-8368
Fax (608) 263-1568