1 July 1998
We have recently mapped a gene for a very rare autosomal recessive disorder
the Rogers Syndrome also known as Thiamine-Responsive megaloblastic anemia.
Clinical symptoms are diabetes mellitus, deafness and megaloblastic anemia,
responding to various degrees to thiamine treatment.
Our best mapping interval is now within a 4cM region on 1q23. We are trying to gather as many as possible affected families to reduce the linkage interval.Is anyone interested to collaborate with us and send DNAs from affected families. It would be of great help.
This project has IRB approval.