We are interested in the molecular genetics of familial neuroblastoma and have an IRB approved protocol for specimen procurement and linkage analysis.
We would appreciate being notified of any patients/families that meet any of the following criteria and whom might be interested in providing a blood sample (archival tumor specimens useful also):
1. Proband with one or more first degree relative with neuroblastoma, ganglioneuroblastoma or ganglioneuroma.
2. Proband affected with and/or with one or more first degree relative with Hirschsprung disease or hypoventilation syndrome.
3. Neuroblastoma patients with any other co-morbid condition (congenital malformations, mental retardation, etc.).
We will be happy to provide additional information. Furthermore, we will send copies of consent and specimen procurement forms at your request.