12 March 1998
We are currently seeking patients for a Phase I clinical gene therapy trial for Leukocyte Adhesion Deficiency.
Leukocyte Adhesion Deficiency patients contain mutations in the CD18
integrin molecule which prevent neutrophil adherence. Patients typically
present at birth with delayed umbilical cord separation, and the disease
throughtout life with severe recurrent bacterial infections, absence of pus at wound sites, gingivitis/periodontitis, and chronic leukocytosis.
We feel this is an exciting potential new therapy for this devasting
Please feel free to contact us if you have any questions. Thank you.