- Genetic Variants In Autoimmunity
Scientists report new genetic associations to four diseases in a large scale collaborative effort.
- New AIDS Risk Factor
More rapid HIV disease progression occurs in individuals who have a specific genetic risk factor.
- Genetic Variation In Hair, Eye, And Skin Pigmentation
Several new genetic associations for human hair, eye and skin pigmentation in individuals of European ancestry are reported.
- Genetic Risk Factor For Colorectal Cancer
Common variants in the gene SMAD7 are associated with an increased risk of colorectal cancer.
- Host Of New Genes Spotted
Scientists have uncovered a complex network of genes involved in the conversion of normal cells to cancerous ones.
- The Future's Bright
Researchers have now linked the tendency for future optimism to activity in a small network of areas in the brain.
- Old Trick, New Dog
A new model of anti-viral response in mammals is presented.
- Gene Essential To Sperm Production Identified
In a study published online, researchers report the identification of a gene that has a key role in the development of sperm.
- Rise And Shine
Researchers have established a causal link between the activity of a particular group of brain cells and transitions between sleep and wakefulness.
- Genes Tell Our Evolutionary Tale
Geneticists have identified a number of genes, for a variety of functions, that show the hallmarks of having been favoured by natural selection in different populations.
- The Brain And Feeding
The activity of several brain areas governing human feeding behaviour is modulated by levels of a single gut hormone in the blood.
- Single-Gene 'Badge' For Stem Cells
Geneticists studying the cells of the human gut have found a gene that seems to be expressed exclusively in mouse adult stem cells of the small intestine and colon
- The Beat Goes On With AKAP18
A protein, known as AKAP18, could help the heart to beat faster in response to adrenaline or noradrenaline.
- Heart Of The Matter
Researchers have developed a strategy to successfully manipulate stem cells into becoming heart muscle cells.
- The Long And The Short Of Fatty Liver
Study reports that not all types of fat are equally harmful.
- Micro-Managing HIV Replication
Cellular microRNAs could help HIV persist by shutting off viral replication and contributing to latency.
- HIV Stuns Immune Cells
A known suppression factor in the immune system increases in HIV-infected individuals on critical immune cells.
- Fountain Of Youth
Researchers have identified the cells that provide an essential survival factor to newly created immune cells.
- The Gene-Mapper's Best Friend
Genetic variants associated with dominant or recessive disease-related traits in dogs can be mapped efficiently and with high confidence.
- NO End To Protein Modification
A new biological signalling molecule is described.
- Mitochondrial Downfall In Parkinson's Disease
The mutation of two genes associated with the development of Parkinson's disease cooperate to regulate mitochondrial function when cells are stressed.
- Effective Gene Silencing
New research shows that small interfering RNAs (siRNAs) can be effective and safe tools for silencing genes in vivo.
- MicroRNAs And Metastasis
A particular microRNA, microRNA-10b (miR-10b), has been found in abundance in breast cancer cells that have the ability to spread to other organs.
- Identifying Self Renewing Cells
Large numbers of adult stem cells can be efficiently obtained from testis, thanks to a newly identified molecule on the cell surface that will allow researchers to tell them apart from non-self-renewing cell types.