- Germ Warfare In Cancer
Article describes how evidence is accumulating to suggest that bacteria that cause persistent infections can directly promote tumour formation.
- Lose The Addiction, Keep The Reward
New research suggests a potential way to decrease the appeal of drugs without affecting motivation for normal rewarding activities, such as eating.
- Regulatory T Cells Checks The Immune System
The April 2005 issue of Nature Immunology examines the state-of-the-art understanding in the biology of regulatory T cells and how they may directly affect many conditions.
- Preeclampsia Susceptibility
A gene associated with susceptibility to preeclampsia is identified, explaining why this condition runs in families.
- Predicting Stroke Risk In Sickle Cell Anemia
A new study provides a predictive model that can identify sickle cell anemia (SCA) patients at risk of stroke with greater accuracy and faster than current methods allow, which may be useful as a prognostic test.
- Wnt Signals Two Ways To A Healthy Gut
The same signal that ensures that there are cells available to keep your intestine replenished also controls a cell type that is required to defend against bacterial infection.
- Human Genes Corrected
Scientists demonstrate a new way to correct disease-causing mutations in human DNA; this could herald an alternative to gene therapy.
- Single Gene Prevents Cartilage Destruction
Two research groups have shown that shutting down a single gene can prevent cartilage destruction in a mouse model.
- New Structural Insights Into RNA Interference
The structural features important for silencing target genes by an RNA-induced silencing complex are reported for the first time by two research groups.
- DNA Repair Enzyme Caught In The Act
Researchers report the chemical structure of an enzyme vital for repairing routine damage to our DNA that is caused by oxidative damage.
- New Insights Into Breast Cancer Predisposition
Mutations in the BRCA2 gene can inhibit the functioning of a mechanism that regulates the activity of the protein encoded by this gene.
- Cause Of Blood Disorder Found
The cause of polycythaemia vera, a blood cell disease linked to leukaemia, is revealed.
- HIV's Early Victims Revealed
Two papers, published online, shed crucial light on the earliest events in the human body after an HIV infection.