your information resource in human molecular genetics
Inheritance Extends Beyond the DNA Sequence Identical twins are more alike than fraternal twins not only because of the similarity of their DNA sequence, but also because the pattern of chemical modifications that regulate expression of their DNA is also more similar.
Stem Cells and Disease Modelling Scientists have generated pluripotent stem cells from the skin cells of a patient with spinal muscular atrophy (SMA), and show that these cells can be used to model the specific pathology for inherited diseases.
Arrestin' Insulin Resistance The protein beta-arrestin-2 helps ensure efficient insulin signalling by scaffolding key enzymes to the insulin receptor.
Natural Killer Cells Never Forget A study reports that certain cells of the innate immune system can 'remember' infectious agents - an ability previously only attributed to cells of the adaptive immune system.